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Genome-wide association study of vitamin D status in diverse ancestry individuals with adjustment for ambient ultraviolet B (UVB) radiation
Background & aim
25-hydroxyvitamin D (25OHD) level, the vitamin D status biomarker, is influ...
Shraim, R., van Geffen, J., McManus, R. and Zgaga, L. | Journal: Clinical Nutrition | Volume: 64 | Year: 2026 | First page: 106746 | doi: 10.1016/j.clnu.2026.106746
Publication
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Ambient ultraviolet-B radiation, supplements and other factors interact to impact vitamin D status differently depending on ethnicity: a cross-sectional study
Background & aims
Many determinants of vitamin D status have been well-described, yet supple...
Brennan, M.M., van Geffen, J., van Weele, M., Zgaga, L. and Shraim | Journal: Clinical Nutrition | Volume: 43 | Year: 2024 | First page: 1308 | Last page: 1317 | doi: 10.1016/j.clnu.2024.04.006
Publication
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Prevalence and determinants of profound vitamin D deficiency (25-hydroxyvitamin D <10 nmol/L) in the UK Biobank and potential implications for disease association studies
Background
25-hydroxyvitamin D (25OHD) is the principal biomarker of vitamin D status. Values be...
Shraim, R., Brennan, M.M., van Geffen, J. and Zgaga, L. | Journal: Journal of Steroid Biochemistry and Molecular Biology | Volume: 250 | Year: 2025 | First page: 106737 | doi: 10.1016/j.jsbmb.2025.106737
Publication
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Genome-wide gene-environment interaction study uncovers 162 vitamin D status variants using a precise ambient UVB measure
Vitamin D status is influenced by genetic and environmental factors-primarily sun exposure. Using...
Shraim, R., Timofeeva, M., Wyse, C., van Geffen, J., van Weele, M., Romero-Ortuno, R. Lopez, L.M., Kleber, M.E., Pilz, S., März, W., Fletcher, B.S., Wilson, J.F., Theodoratou, E., Dunlop, M.G., McManus, R. and Zgaga, L. | Journal: Nature Communications | Volume: 16 | Year: 2025 | First page: 10774 | doi: 10.1038/s41467-025-65820-x
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Comprehensive Analysis of Seasonal and Geographical Variation in UVB Radiation Relevant for Vitamin D Production in Europe
Dermal synthesis, following sun exposure, is the main source of vitamin D. This study characteriz...
Khanna T, Shraim R, Zarkovic M, van Weele M, van Geffen J, Zgaga L. | Journal: Nutrients | Volume: 14 | Year: 2022 | First page: 5189 | Last page: 5204 | doi: 10.3390/nu14235189
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